The Cannabis industry is a fast-paced and quickly evolving landscape. With regulations changing constantly at state and local levels and federal regulation on the horizon, seed-to-sale operators navigate shifting standards and guidelines. By employing an ERP system, cannabis operators have the build-in ability to succeed in this landscape.

What is Inventory Management Software?

An Inventory Management System tracks and manages inventory items at all points including purchase, storage, production and sale. Inventory Management Software allows for digital traceability optimizing visibility, compliance and informing operational stock levels.

What is an ERP System?

An ERP system is a comprehensive management platform that integrates all functionalities of an operation into a single system. All core processes are streamlined in order to improve productivity, enhance profitability and enable smart growth. Purchasing, inventory, sales, production, compliance, HR and finance are unified into a single source of truth resulting in streamlined workflows, data-driven decision-making and the ability to effectively adapt at a moment’s notice.

Why do Cannabis Operators need an ERP System?

Cannabis operators — including cultivators, extractors, distributors and point of sale merchants — benefit from an ERP system in all ways. By streamlining operations, digitizing data, and connecting all aspects of their operation into a single source of truth, companies automatically improve efficiency, profitability and compliance.

Top Cannabis ERP Software Systems in 2025

WHEREFOUR

Wherefour has been partnering with seed-to-sale operators since 2015. Offering tailored integrations, ensuring start-to-finish traceability, and streamlining compliance, Wherefour’s cloud-based ERP suite is a premier solution in the cannabis industry.

Features

Inventory & Production Management: Cloud-based accessibility that monitors and records stock levels, warehouse locations, barcodes, automated reorder points, FIFO/LIFO/FEFO, COGs, user data with end-to-end traceability

Compliance, Recall Reports & Lot Code Traceability: Customizable platform with QA tests, recall report capabilities, automatic bundling of COAs, lab test results, shipment phones, scanned notes, PDFs and more

Sales/CRM: Workflow integration with Shopify, ShipStation and more enables streamlined access to customer records, payment terms and shipping instructions making fulfillment fast, secure and accurate

Accounting Integrations: With direct integrations to QuickBooks, Sage Intacct, Microsoft Dynamics, Xero and more, all financial records are automatically synced and secure

B2B & Ecommerce Automation: Empower your customers with access to the customizable B2B portal and automate ecommerce fulfillment with automatic import capabilities

Traceability: From raw materials to finished goods, end-to-end traceability enables accuracy and transparency for day-to-day operations and regulatory compliance

Analytics & MRP: Enterprise-grade functionality available at a personalized level with MRP analytics at the touch of a button

Customer Success Team: A committed team of professionals are devoted to implementation offering one-on-one access to troubleshooting and customized solutions

Contact Wherefour for more information on pricing, functionality, and to receive your customized demo today!

ACUMATICA

Acumatica offers seed-to-sale ERP software for cannabis, hemp and CBD businesses.

Features

Production, compliance and supply chain integration workflows

Cloud-based accessibility on desktop and mobile devices

Enterprise-grade, built for large operations

Learn more about Acumatica

BACKBONE

Backbone is a supply chain management platform built for cannabis operators.

Features

Supply chain, compliance and financial integration workflows

Customizable software and hardware integrations for operational automation

Enterprise-grade, built for large operations

Learn more about Backbone

365 CANNABIS

365 Cannabis is seed-to-sale software for compliance and cannabis ERP functionality.

Features

Vertically integrated modules for financials, cultivation, processing, CRM, distribution and retail

Cloud-based accessibility on desktop, tablet and mobile

Powered by Microsoft, enterprise-grade

Learn more about 365 Cannabis

Cannabis operators who employ an ERP system have a clear advantage in the fast-paced, quickly changing landscape. With dynamic capabilities that integrate, streamline and unify all aspects of their operation, companies are poised for day-to-day success and long-term growth.